Research Assistant I
Department Description: The Kirby laboratory (https://www.kirbylab.org) is seeking a Research Assistant to begin starting ideally in June-July, 2021 to help develop new antibiotics for multidrug-resistant bacterial infections, and understand resistance mechanisms such as efflux pumps and learn how to thwart them. We perform studies to understand the mechanism of action and effects of novel antimicrobials on a wide range of bacterial pathogens, especially Gram-negative pathogens such as carbapenem-resistant Enterobacterales, Acinetobacter baumannii, Pseudomonas aeruginosa, and others. Many techniques are used including molecular biology, microbiology, bacteriology, next generation sequencing, CRISP-based mutagenesis, tissue culture, cloning, Tn-Seq, bioinformatics, inkjet printing-based high throughput susceptibility testing assays, and protein analysis. We also work in close collaboration with medicinal chemists and structural biologists so that we can attack antibiotic resistance from multiple different angles. All of the work in the laboratory is highly collaborative and has direct medical translation. Help us address the antibiotic resistance crisis! I expect the Research Associate to be involved in several projects. We welcome motivated applicants who wish to learn a lot about biology and experimental techniques. Recent or upcoming college graduates who wish to pursue future graduate school or medical school studies are especially welcome to apply. Prior research experience would be considered a strong asset. We provide mentorship for motivated students to develop a deep immersion in the research laboratory that will set the stage for application to graduate school, and future careers as scientists and/or physicians. Please apply through the BIDMC website.
Job Location: Boston, MA
Req ID: 39959BR
Job Summary: Under supervision of the principal investigator, conducts a variety of routine experiments using molecular, cell biology and/or biochemistry techniques. Records test results, calculates, transcribes, and analyzes data using basic statistics.
- Conducts routine tests following established procedures, which may include assays, DNA sequencing, tissue culture, protein purification, Southern blotting, PCR analysis, electrophoresis, chromatography.
- Researches and collects basic study data through monitoring devices and maintains daily logs/basic records of methodologies and test results. With supervision, using databases, may summarize data and interpret results using descriptive statistics and basic hypothesis testing.
- May write standard operating procedures for documentation and make informal presentations of these procedures to others in the lab.
- Performs literature searches and library investigations as they relate to the research and/or as assigned.
- Due to the dynamic environment in which research exists, must show flexibility in performing principal duties and responsibilities as research projects evolve.
- Bachelor's degree in Biology, Biochemistry, Life Science or a related scientific field required.
- 0-1 years related work experience required.
- Familiarity with basic laboratory instruments and equipment, computers (databases, spreadsheets, statistics) and scientific procedures.
- Basic familiarity with computers. Ability to navigate at a basic level within web-based applications.
- Decision Making: Ability to make decisions that are based on specific instructions, standard practices and established procedures which generally require little or no supervision.
- Problem Solving: Ability to address problems that are routine, somewhat repetitive and generally solved by following clear directions and procedures and by identifying opportunities for process improvements.
- Independence of Action: Ability to follow general instructions and procedures as provided. Work is monitored by supervisor/manager.
- Written Communications: Ability to communicate clearly and effectively in written English with internal and external customers.
- Oral Communications: Ability to understand spoken English in order to follow basic safety instructions and take direction from supervisors; communicate effectively in basic English with patients, families and medical center staff in response to routine questions.
- Knowledge: Ability to demonstrate basic knowledge of fundamental concepts, practices and procedures with the ability to use them in routine situations. Specialized knowledge not required.
- Team Work: Ability to interact respectfully with other employees, professional staff and/or external contacts to offer ideas, identify issues, obtain information or deliver services.
- Customer Service: Ability to demonstrate a positive attitude and respond to requests in a timely and respectful manner.
Physical Nature of the Job:
Light work: Exerting up to 20 pounds of force frequently to move objects. Some elements of the job are sedentary, but the employee will be required to stand for periods of time or move through out the hospital campus
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