Research Assistant I
Department Description: The Pollak laboratory studies inherited kidney disease using human genetics, transgenic mouse models, and molecular biology. We use cutting edge techniques such as CRISPR-transgenic mice, RNA sequencing, and super-resolution microscopy to understand how genetic variants in the APOL1 gene cause kidney disease in African Americans. Our research environment is highly collaborative and includes projects and meetings with a wide range of other research groups, providing exposure to new ideas and opportunities to learn new techniques.
Job Location: Boston, MA
Req ID: 41304BR
Job Summary: Exciting opportunity to work on a team project that utilizes transgenic mouse models to understand and treat kidney disease. The ideal candidate will have lab experience and good problem-solving skills. Under the supervision of the principal investigator, conducts a variety of experiments using molecular, cell biology and/or biochemistry techniques. Records test results, calculates, transcribes, and analyzes data using basic statistics. Opportunities to learn a broad range of experimental and analytic methods. Similar jobs have provided many of our previous employees with a fun, interesting, and educational experience before attending medical school or graduate school.
- 1. Helps maintain a colony of transgenic mice, which may include setting up breeding pairs, weaning, ear tagging, and tailing.
2. Performs a variety of mouse experiments
3. Conduct assays, which may include DNA sequencing, tissue culture, western blotting, PCR analysis, immunohistochemistry, ELISA, and qPCR.
4. Researches and collects basic study data through monitoring devices and maintains daily logs/basic records of methodologies and test results. With supervision, using databases, may summarize data and interpret results using descriptive statistics and basic hypothesis testing.
5. May write standard operating procedures for documentation and make informal presentations of these procedures to others in the lab.
6. Performs literature searches and library investigations as they relate to the research and/or as assigned.
7. Due to the dynamic environment in which research exists, must show flexibility in performing principal duties and responsibilities as research projects evolve.
- Bachelor's degree in Biology, Biochemistry, Life Science or a related scientific field required.
- 0-1 years related work experience required.
- Familiarity with basic laboratory instruments and equipment, computers (databases, spreadsheets, statistics) and scientific procedures.
- Basic familiarity with computers. Ability to navigate at a basic level within web-based applications.
- Decision Making: Ability to make decisions that are based on specific instructions, standard practices and established procedures which generally require little or no supervision.
- Problem Solving: Ability to address problems that are routine, somewhat repetitive and generally solved by following clear directions and procedures and by identifying opportunities for process improvements.
- Independence of Action: Ability to follow general instructions and procedures as provided. Work is monitored by supervisor/manager.
- Written Communications: Ability to communicate clearly and effectively in written English with internal and external customers.
- Oral Communications: Ability to understand spoken English in order to follow basic safety instructions and take direction from supervisors; communicate effectively in basic English with patients, families and medical center staff in response to routine questions.
- Knowledge: Ability to demonstrate basic knowledge of fundamental concepts, practices and procedures with the ability to use them in routine situations. Specialized knowledge not required.
- Team Work: Ability to interact respectfully with other employees, professional staff and/or external contacts to offer ideas, identify issues, obtain information or deliver services.
- Customer Service: Ability to demonstrate a positive attitude and respond to requests in a timely and respectful manner.
Physical Nature of the Job:
Light work: Exerting up to 20 pounds of force frequently to move objects. Some elements of the job are sedentary, but the employee will be required to stand for periods of time or move through out the hospital campus
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